Although manufacturing processes vary widely, a typical fiber optic production process uses large quantities of helium that is controlled by oxygen transmitters or analyzers.

In the fiber manufacturing process, helium is essential for cooling fiber as it is being pulled from a furnace and prior to applying protective coatings. Helium enhances heat transfer and provides the stable inert atmosphere necessary for increased productivity by preventing the burning element from burning up during the process.

In some processes nitrogen is used instead of helium.

In critical telecommunications applications with irreplaceable assets inert gas is used in fire suppression systems where it displaces oxygen in order to extinguish the fire.